The present study examines the relationship between Small and Medium Sized Enterprises (SMEs) and Six Sigma methodology, recognizing the importance of SMEs in global economies. It is difficult for SMEs to seamlessly implement new processes due to a lack of resources. Developed in the manufacturing sector, Six Sigma emerges as a systematic approach to defect minimization. It is, however, critical to navigate the challenges SMEs face strategically in order to integrate successfully. Using an extensive literature review from 2012 to 2023, this paper examines the challenges and opportunities of implementing Six Sigma in SMEs. Using existing research, the paper synthesizes frameworks, models, and best practices for implementing Six Sigma in SMEs.

A comprehensive resource will be established for Six Sigma implementation in SMEs, addressing the literature gap specific to SME contexts. Using systematic literature reviews, the paper answers key research questions and identifies Six Sigma implementation models and frameworks. A discussion of the strengths and weaknesses of recent models is presented in the results and discussion section. To conclude, the paper emphasizes the importance of inclusive models for SME growth and encourages future research to expand its scope.