Quality 5.0 refers to the transition from technology-driven quality management systems to human-machine collaborative value creation, with an emphasis on environmental sustainability, ethical AI use, and employee well-being.  Despite the increased interest in this concept, this research found no analysis specifically focused on South Africa's positioning or potential for transition to Quality 5.0.   Because of differences in infrastructure, economics, technology, and policy, nations with developed economies may be able to transform more easily than developing/underdeveloped countries.  This study addresses this gap in the literature by conducting a SWOT analysis of Quality 5.0 implementation in South Africa.  The Delphi approach is used in the study to achieve this.  The study revealed three critical strengths: an existing proactive quality culture, alignment with socio-ethical principles, and leadership commitment. The analysis then identified the country's primary shortcomings as energy and infrastructural vulnerabilities, employee and societal resistance, and economic instability.  The study discovered that the main benefits of adopting Quality 5.0 were sustainable product development, sustainable growth, meeting societal demands, and improving product quality, while the main threats were political instability, cybersecurity risks, and a lack of standardization.  This study provides critical insights for businesses attempting to implement Quality 5.0 in identifying their strengths and limitations on their path to embracing the advantages of Quality 5.0 initiatives.  This study supports the United Nations' Sustainable Development Goals.