The application of information technology in the health sector is increasingly experiencing intensive development because improvements are needed for the medical world through the application of technologies and programs that are appropriate for the benefit of therapy, care and process monitoring. In this research, the team will carry out the design process of monitoring infant health using SMS-based information technology. The purpose of this study is to provide a solution so that babies born can undergo the immunization process properly using a special application and is equipped with a design such that it is easy to use, operated based on an SMS gateway. So that mothers and babies are born always get accurate information about immunization activity until the baby's age limit is exactly 59 weeks and without errors. SMS gateway based applications can be implemented in health centers or hospital services. This application has a range of up to several cities in the vicinity which are close to health care centers or hospitals that are responsible for providing the fastest service.