Entrepreneurship courses can be vital in facilitating an entrepreneurial ecosystem among Universitas Negeri Medan students. An entrepreneurial ecosystem can be formed because the university itself has students from various disciplines who are allowed to have a meeting of demand and supply. This dynamic offers collaboration between entrepreneurs by creating a value chain between them to grow together. This study will focus on developing standard manuals related to the achievement of Universitas Negeri Medan entrepreneurship learning, namely, determining the situation of entrepreneurial learning practices in initiating students to establish their own business through entrepreneurship courses. This study uses a quantitative approach to survey research methods. The sample in this study were Universitas Negeri Medan students using a questionnaire online. The questionnaire was filled in by contacting the respondents via cellular phone as many as 108 respondents. The results show that of the seven question items as a whole still do not answer the needs of students in creating and developing entrepreneurial learning practices in initiating students to have the ability to be entrepreneurial independently.