This paper proposes a new multi-criteria decision making model to evaluate product design alternatives. It enables us to evaluate architecture of a new product by considering different criteria relating to product, process, and supply chain design. The model also uses life cycle assessment to evaluate alternatives. To deal with the vagueness of some data used in life cycle assessment, fuzzy set theory is employed. A real case is used to illustrate the efficiency of the model. In final, the conclusions and future research directions are proposed.