Air cargo in African countries plays a relevant role in developing intra-African trade and enhancing economic prosperity. Unlike its great potential and expansion in foreign countries, Africa remains the weakest region worldwide. In 2016, according to ICAO’s forecast, scheduled air traffic Compound Average Annual Growth Rate (CAGR) in Africa will reach 2.2 percent Freight Tonne Kilometre (FTK) by 2042 while world air cargo will grow over the next years by 4.2 percent per year.  Despite of several researches related to airfreight industry little have analysed the factors influencing the growth of African air cargo market. This paper aims to fill a gap of literature by identifying the factors leading the development of African air traffic. Moreover, an insight is provided into the actual five cities concentrating the intra-African network namely, Cairo, Johannesburg, Nairobi, Addis Ababa, and Lagos. The results and interpretations have a significant importance for aviation stakeholders who aim to enhance airfreight’s flow in African markets.