Indonesian’s population is one of the highest in the world and create a potential market in the service industry especially healthcare. By the end of 2019, 85% of world business plans will implement Internet of Things (IoT). Implementation of IoT was driven by business innovation and business efficiency. This paper aims to establish a framework to integrate Internet of Things in healthcare industry especially hospital, in order to improve the overall quality of healthcare processes. Six experts’ opinions are used to identify the relationship and select the factors and sub factors that support the integration of Internet of Things in Indonesian hospital. Analytic Network Process (ANP) method is used to obtain the decision priority of healthcare practices supported by the implementation of Internet of Things. Zero-One Goal Programming (ZOGP) method is used to choose which healthcare practices will be implemented based on the optimal number of IT’s employees, decision priority of ANP, procurement cost, installation cost, training cost, maintenance cost constraints. The case study was conducted to private and public hospitals in Jakarta.