This study investigates the musculoskeletal problems in four craft sectors in the Jaipur, India, namely carpet washing, trimming, alignment and wood carving. A field study was conducted in 13 workshops of several handicraft manufacturers, and 122 male respondents were randomly selected for the survey. The data about pain occurrence at different body and hand regions among the participants were collected using a questionnaire. Mean perceived exertion among the handicraft workers during respective craft tasks was estimated according to Borg’s rated perceived exertion (RPE) scale The highest prevalence of symptoms in the body regions was reported for the last 12 months were the Wrist, Lower back, Shoulders. Whereas, metacarpal, thenar eminence, and hypothenar were the most prominent hand regions of discomfort. These discomfort regions could be due to the poor workstation and hand tool design, and awkward working postures. Furthermore, the study revealed that the mean scores of the RPE were significantly higher with higher age and experience. It can be postulated that the work system including hand tools should be redesigned that may reduce the symptoms of musculoskeletal disorders. Health habits also play a role in RPE, albeit to a moderate degree.