This study aims to obtain empirical evidence regarding entrepreneurial activities carried out by students at several universities in Indonesia, both public and private universities based on gender. This research involved various driving factors including entrepreneurship education before entering college, entrepreneurial experience before entering college, and entrepreneurial orientation of each male and female student. The survey was conducted at 18 universities in Indonesia by obtaining data from 456 respondents. The data analysis techniques were contingency testing using SPSS20 to compare the relation students background and student entrepreneurial activity with gender as the control variable, and confirmatory factor analysis using AMOS22 to analyze the tendency of entrepreneurial orientation of female students and male students. Empirical evidence states that gender has an important role in the relationship between students' entrepreneurial experiences before entering college with the level of entrepreneurial activity carried out by students, while the entrepreneurial education they got before entering college does not have a significant relationship with student entrepreneurial activities. This proves that entrepreneurial learning which is only based on knowledge does not have positive implications compared to direct entrepreneurial experience. The results of this study provide suggestions for decision-makers in universities that the provision of an eclectic entrepreneurial learning ecosystem will have more implications for entrepreneurial activities for students.