Pesantren has some uniqueness when compared with other educational institutions. This article aims to study the role of the Pesantren Darul Huffadh Tuju-Tuju in building the character of santri based on the Quran and local wisdom. This research applies a qualitative approach. Through interviews and observations, data collection is supported by written sources and strengthened by the author's intensive interaction with the director and alumni. The results show that this pesantren is unique. It requires all of its students to memorize the Quran as its main characteristic since its establishment until now. The strength of the pesantren is in the strong character attached to the figure of K.H. Lanre Said. His style is a blend of the main principles of the Quran and the local wisdom. The combination of religious background and social strata supports him with a strong character, which becomes a role model for the pesantren community. The central values underlying the character are taught to his children and students through exemplary 'taro ada taro gawu' and sublime messages. For Darul Huffadh, building the character of religious moderation must be built from three things: well understanding of the Quran, mastery of the basic Islamic sciences, and strengthening local wisdom values.