This research addresses inefficiencies in Peruvian textile SMEs, focusing on improving sewing operations. Existing studies highlight the effectiveness of Lean Manufacturing and Total Productive Maintenance (TPM) in enhancing productivity, but few examine their application in textile SMEs. The case study implemented SMED to reduce setup times and autonomous maintenance to minimize machine downtime, combined with linear programming to optimize production scheduling. The study yielded significant results: sewing efficiency improved by 26.80%, setup times decreased by 30.97%, and machine downtime reduced by 33.83%. These outcomes validate the integration of Lean and TPM as an effective solution for enhancing operational performance in textile SMEs. Academically, this research contributes to the growing body of knowledge on Lean and TPM in small enterprises, while socio-economically, it promotes competitiveness and sustainable growth in the Peruvian textile sector. This study encourages further research on adapting Lean and TPM tools to various industries, emphasizing the need for continuous improvement in operational efficiency.