In the competitive landscape of modern manufacturing, validating shop floor configurations prior to implementation is crucial for minimizing risks and ensuring operational efficiency. Value Stream Management (VSM) is defined as a holistic management approach for mapping, analyzing, designing, and implementing waste-minimized value streams. This paper explores the application of a Digital Value Stream Twin (DVST), mainly focusing on the data- driven design and validation of shop floor configurations. Within this framework, a value stream model expanded to include the dimensions of costs and sustainability is used. The related key figures are considered as part of the scenario assessment to account for various company objectives. By leveraging a fischertechnik® Training Factory Industrie 4.0 environment and utilizing Arena® for simulation, the potential of DVST in creating optimal shop floor configurations is investigated. The results demonstrate the benefits of using DVST to enhance accuracy, flexibility, and decision-making in manufacturing environments.