This study targets enhancing profitability in a Peruvian construction company through the integration of Total Productive Maintenance (TPM), Lean Manufacturing and Human Resources Management tools. Historically, the construction sector in Peru has faced challenges such as material shortages, labor inefficiencies, and operational disruptions due to socio-political unrest, contributing to a profitability decline. This research responds to these challenges by proposing a model that applies Lean tools—Just-In-Time for material procurement efficiency, Total Productive Maintenance and Autonomous Maintenance for improved machinery reliability, and Standard Work and One-Point-Lesson for labor productivity. Additionally, a human resources strategy was designed to address the inadequate management and training of labor forces. The implementation of this model significantly improved operational outcomes, as evidenced by four key performance indicators: Profitability increased from 3.8% to the targeted 8%, Machinery availability enhanced, reducing downtime and operational delays, Maintenance compliance achieved 100%, and Labor productivity increased by 79%, demonstrating a substantial reduction in labor-related inefficiencies. These results underline the effectiveness of combining TPM y Lean Manufacturing principles with strategic human resources management to tackle the root causes of inefficiency in construction operations, positioning the model as a benchmark for similar companies in culturally and geographically analogous settings.