This research focused on designing and validating a Digital Transformation Maturity Model tailored to the manufacturing sector in Latin America. The study utilized a mixed-methods approach, incorporating qualitative tools such as focus groups and interviews, along with quantitative data from audits and key performance indicators. A multiple-case study methodology was implemented, applying the model iteratively to four manufacturing companies in Nuevo León, Mexico. Key phases included problem identification, theoretical foundation through a literature review, iterative model redesign based on empirical feedback, and validation of its applicability. The result was a consolidated maturity model, supported by a strategic roadmap to guide organizations toward higher levels of digital transformation maturity. This work contributes a structured, evidence-based framework to address the challenges and opportunities of Industry 4.0 in the region.