In the dynamic landscape of smart manufacturing, traditional Quality Management Systems (QMS) often fail to meet the demands for agility, real-time responsiveness, and scalability. This article introduces a Hybrid QMS framework that integrates foundational quality practices with advanced technologies, including IoT, cloud computing, and data analytics. The Hybrid QMS facilitates real-time quality monitoring, agile interventions, and cross-site scalability, leveraging modular architecture for incremental upgrades. This approach merges traditional quality protocols with modern interconnected systems, enhancing efficiency, adaptability, and resilience. With profound implications for Industry 5.0, the Hybrid QMS fosters human-machine collaboration and proactive quality management, offering a transformative solution for data-driven, scalable quality control in complex manufacturing environments.