In the rapidly evolving landscape of supply chain management, the emergence of Industry 4.0 technologies has ushered in a new era of transformation. This study explores the deep effects of Industry 4.0 on supply chains by analyzing the incorporation of state-of-the-art technologies. It offers a thorough conceptual framework for supply chain management's implementation of Industry 4.0, highlighting how it aligns with corporate goals, sector-specific requirements, and international best practices. This paper explores the integration of Industry 4.0 technologies into supply chain management, focusing on the impact of the COVID-19 pandemic. A qualitative research approach was adopted, consisting of a systematic literature review. The literature review covered key technologies such as the Internet of Things (IoT), artificial intelligence (AI), big data analytics, blockchain, and augmented reality (AR) to understand their relevance in transforming supply chains. The findings highlight the potential of Industry 4.0 to improve visibility, agility, and resilience in supply chains, offering both theoretical insights and practical guidance for industry practitioners seeking to navigate the challenges of the digital era.