The leather chemical industry in Bangladesh plays a pivotal role in supporting the nation’s leather sector, which encompasses tanneries, footwear, and leather goods. It contributes 3% to GDP and generates $1.1 billion annually in exports. This study examines the current market dynamics, key drivers, and challenges shaping the leather chemical industry while forecasting its future prospects. Data were collected through structured questionnaires targeting leather manufacturers and chemical suppliers, as well as in-depth interviews with professionals. The analysis explores market trends, adoption of sustainable practices, environmental impacts, and the influence of government initiatives. The analysis revealed that over 50% of participants prefer eco-friendly or hybrid chemicals, indicating a shift towards sustainable practices driven by global trends and consumer demand. However, the transition faces challenges, including increased production costs, reported by 40% of respondents, and external barriers to implementation. This study underscores the need for strategic investments in technology, workforce training, and infrastructure to address current limitations and capitalize on emerging opportunities.