This work aimed to assess an industrial workspace’ sustainability and employees’ well-being. A comprehensive approach was adopted, including data collection, field audits, and detailed measurements of indoor environmental quality—focusing on thermal, visual, and acoustic comfort, and indoor air quality. Employee feedback was also gathered through surveys to provide subjective assessments of office conditions. The results revealed the need for adjustments to improve thermal comfort, where thermostat settings and airflow required modification. Visual comfort was generally satisfactory, though task lighting was recommended in selected zones. Acoustic discomfort was identified as a major issue across the office, necessitating noise awareness initiatives and using sound-absorbing materials. Furthermore, indoor air quality concerns were raised in several zones, with recommendations including a fresh air ventilator, occupant density reduction, and rigorous maintenance implementation to prevent air contaminants. Energy performance assessments conducted between October and November 2022 identified substantial opportunities for energy conservation. Recommendations included installing timers for air conditioning systems, lighting, and office equipment, along with optimizing chiller and pump operation schedules. Implementing these measures could result in annual energy savings of 152,282 kWh, cost savings of 4240 OMR, and a reduction of 163.8 tons of CO₂ emissions. Additional recommendations include establishing a sustainability team, installing separate utility meters for more accurate monitoring, and deploying photovoltaic systems for energy generation. These strategies aim to enhance the office’s sustainability without compromising occupant well-being, aligning with both current and future office design goals.