This study will examine the impact of economic, environmental, social, and technical factors in reverse logistics, as well as present a summary of significant drivers and barriers that have the potential to stimulate or deter enterprises from implementing reverse logistics methods. In the last half century, MSME sector has grown as a tremendously lively and competitive segment of the Indian economy. However, most research does not focus on this sector. To bridge this gap, this study identifies and evaluates the critical factors of Reverse logistics in the Indian MSME’s. From a systematic literature review a list of critical factors in Reverse logistics were identified and a questionnaire was developed to conduct a survey in 36 Indian MSME’s to assess their efficiency in Reverse logistics. Data Envelopment Analysis (DEA) methodology was applied to the data collected to identify the important Reverse logistics enablers and barriers. This methodology can also be used to assess the efficiency of the reverse logistics model, as well as to increase efficiency by altering critical factors. Key performance Areas such as Performance management system, Latest technologies, Volume of products, financial investment are the key performance inputs to be given more importance for the inefficient companies to become efficient. Awareness of Reverse logistics, Complexity of operation and third-party logistics are the output variables to be concentrated for the inefficient companies to match the benchmark companies. It can be further extended to other states and countries so as to make cumulative study among the region