Safety has been said to be the priority in all sectors of society. Although safety has been a priority, there has been an emerging trend of unsafe acts involving Gen Z Filipinos (PSA, 2022). The emergence of unsafe acts of Generation Z Filipinos have been unnoticed (Dela Peña, 2023), this study will provide data on understanding factors influencing behavioral intentions in safety culture. The study aimed to investigate the factors that influence behavioral intention in safety culture among those born within Gen Z. The utilization of Theory of Planned Behavior, Protective Motivation Theory, and Three Broad Domains of Ergonomics will help greatly in the assessment of factors. A survey questionnaire was constructed with various variables such as Risk Perception, Safety Knowledge & Practices, Technology Use, Perceived Behavioral Control, Social Norms, Attitude toward the Behavior, Perceived Severity, Perceived Vulnerability, Physical Ergonomics, Cognitive Ergonomics and Macro-Ergonomics are taken into account. The utilization of Structural Equation Modeling (SEM) helped in investigating the relationship between variables. There was a total of 505 respondents which answered the survey questionnaire. The results showed that the latent variables Risk Perception, Safety Knowledge & Practices, Perceived Vulnerability, Social Norms, Attitude toward the Behavior and Macro-Ergonomics were all factors that have a significant impact to the Perceived Behavioral Intention in Safety Culture of Gen Z Filipinos. The findings can be used to inform and develop policies to improve the safety culture of Gen Z Filipinos.