The research aims to develop a locally designed airborne pathogen detector system for airport entry points in Zimbabwe with the aim to curb airborne diseases before they become a pandemic. The observation came about after the world was affected by covid 19 and the cholera outbreak affecting our neighbour Zambia. The traditional methods, often lab-based and time-consuming, hinder swift responses. Real-time airborne disease detection technologies offer a game-changer, promising rapid on-site results. This review dives into the cutting-edge of real-time detection, exploring diverse technologies and their potential applications. We discuss the challenges and opportunities associated with these advancements, paving the way for future research and development. The system will be monitoring in real time taking advantage of emerging technologies such as Artificial Intelligence, Cloud Computing among others. The results will be noted and analysed giving outputs that will be used either to act or ignore. The conclusions, recommendations will be made and indications on where the system needs improvement for future engineering and technical developments.