Abstract

Neurothekeomas are benign neoplasms that typically present as solitary slow growing nodules on the head and neck. Historically they have been divided into cellular, myxoid, and mixed subtypes. We describe the clinical and pathologic findings of a 44-year-old female with a cellular neurothekeoma arising in association with a nerve sheath myxoma (also known as the myxoid variant of neurothekeoma) on the right parietal scalp. While in recent literature the terminology separating these two neoplasms has diverged due to their different clinical, immunohistochemical, and molecular features, this case provides an interesting counterexample. These findings raise the possibility that these two entities may exist on a histopathologic spectrum.