A timely delivery is a basic requirement of customer these days and becomes an annoying parameter for them if unfulfilled. The purpose of this paper is to present a case study of an e-commerce industry which was struggling towards the timely delivery for their premium subscription customers. A systematic approach of Six Sigma methodology was used to optimize the scenario. This paper showcases the detailed review and analysis of the problems faced by the e-commerce industry using various six sigma tools and techniques including design of experiments. During the project, more than 100 data points were studied and more than 800 data sets were analyzed initially to identify and further to analyze the problem. The paper also emphasizes the approach of problem solving using the six-sigma methodology for the practitioners as well as academic researchers.