Covid-19 pandemic brought several changes in the working conditions of employees, who had to adapt to new work modalities known as home office. The objective of this study was to identify the correlation between the physical and psychosocial ergonomic conditions of the home office environment of workers belonging to the service sector in Peru and the effects of these conditions on their job satisfaction. For this purpose, a quasi-experimental methodology was designed with a mixed approach and a correlational scope, the ergonomic evaluation of the LEST method and a job satisfaction questionnaire were used on a sample of 97 employees in the service sector in Peru. After performing the Pearson correlation using SPSS software, the hypothesis is rejected and, therefore, the alternative hypothesis is accepted, which confirms the existence of a correlation between the variables described before. An inverse and statistically significant correlation was found between the mental workload dimension of the LEST method and job satisfaction.