Hypertension is one of the main problems in the world of public health, both in Indonesia and the world. One treatment to be applied to manage it is non- pharmacological treatment of reflexology. This study aims to determine the effect of reflexology on blood pressure among patients with hypertension in the work area of Kertajati CHC, Majalengka District. This was a quasi-experimental study with one group pretest-posttest design. There were 20 samples involved in this study, namely those with hypertension in the work area of Kertajati CHC, Majalengka District. This study was conducted in the work area of Kertajati CHC, Majalengka District from June 3 to July 3, 2021. The data were analyzed using univariate analysis with frequency distribution and bivariate analysis with Wilxocon test. The results showed that before reflexology, less than half (35.0%) of patients with hypertension experienced stage II hypertension. Furthermore, after reflexology, a small proportion (15.0%) of patients with hypertension experienced stage I hypertension. There was an effect of reflexology on blood pressure among patients with hypertension in the work area of Kertajati CHC, Majalengka District in 2021, as evidenced by a p value of 0.000. It is recommended for the CHC to perform reflexology as an alternative treatment for hypertension. In Addition, there is a need for healthcare workers to provide counseling along with the guidance and supervision to patients with hypertension on how to do reflexology.