This case study conducts on finding the reason behind not moving multinational companies (MNCs) industries or branches in the Rajshahi district based on dominant locating factors of leading MNCs of Bangladesh. Despite Rajshahi’s cultural heritage of textile industries, sugar industry, food manufacturing industry, plastic industry, and research institutes, this city lacks significant multinational companies, unlike other divisional cities. In this paper, major locating factors of leading multinational companies in Bangladesh were investigated through ‘TOPSIS Analysis’, and easy transportation was come up with the main locating factor. Then ‘Thematic Analysis’ was used for qualitative data analysis, and here transportation facilities were found to be the principal reason behind not moving to the Rajshahi district. ‘Google Earth’ was used to exhibit the transportation route of different cities and compare these routes with Rajshahi’s distribution center. It was found that, a gateway through a water path in the Padma river could open a new door for MNCs to locate their factories or branches in the Rajshahi district.