The aim of this study was to show what was caused by Covid-19 at all stages of the food supply chain, whose actors are: producers, processors, distributors, retailers and consumers. Likewise, it sought to identify the main problems and the response actions of each link in the face of the new conditions of the pandemic; for this, a systematic review of the literature was carried out, which was based on the collection of knowledge regarding Covid-19 and the food supply chain. As a result of this search, 67 papers from reliable databases were collected, databases such as Scopus and Web of Science; these papers were considered because they met the stipulated inclusion criteria. The selected papers allowed to identify that the main problems in the links are due to the shortage of labor / workforce, difficulty in the supply of materials or inputs, lack of transportation to distribute food and products, fluctuation in demand and price increases. Regarding the first links, it is identified that the majority of response actions were deeply linked to technology, innovation, IoT, automation and optimization, seeking to reduce the involvement of labor; and, in the case of the consumer link, the response actions were linked to the use of virtual platforms. These responses were adapted in various ways depending on the link, since each of them acted differently to each problem; despite this, the decisions to be made should consider the repercussions they would have on the next link.