Human trafficking that occurs in vulnerable groups such as women is a crime that violates human rights. Until now, the practice of buying and selling human beings, especially women, continues to multiply, especially in the pattern of victim screening. The reality is that the Covid-19 pandemic has not reduced the number of cases of trafficking in women who have socially experienced various inequalities and particular vulnerabilities due to their marginal social position, thus making them entangled in indications of trafficking in women that dominate and pose a significant threat. The study of intersectionality is considered capable of seeing the different situations faced by women and marginalized groups. It becomes a meeting point study on gender issues, especially during the current pandemic, which shows the increasing cases of trafficking in women. And the purpose of this research is to explain the form of handling the crisis of trafficking in women with intersectionality law regulations. This study uses a qualitative method by collecting data on intersectionality law regulations through report documents, literature, news, and journalism related to the research. Data analysis used the Nvivo12 Plus qualitative data processing application with crosstab query tools analysis and cluster analysis group. Furthermore, the study results show that intersectionality legal regulations refer to gender equality. However, these regulations are still ineffective and still discriminate against women or are less gender-sensitive to suppress the spread of cases of trafficking in women. The vulnerable sector is shown in the sex trade, worrying, especially during the current pandemic. Based on the study results, it is concluded that there is a need for new legal regulations regarding intersectionality that provide legal construction as a basis for women in fighting against unfair hegemony and guaranteed in various legal instruments, both international and national law.