This paper presents the results of a research questionnaire of building occupants in selected commercial and office buildings in Hyderabad. A total of 614 building occupants participated in the study from selected 28 commercial and office buildings. Many researchers have used questionnaire as an effective tool to measure the comfort of building occupants. Hence, teams were formed for conducting the questionnaire survey in different buildings. The occupants were explained the purpose of the study and asked to give their feedback on the form. The data was collected and analyzed to know their level of satisfaction with the building environment. Results show that the participants were mainly young males who spend a considerable time indoors. HVAC system is operational for most part of the year in those buildings. Some occupants have reported health issues like nasal irritation, headache, throat irritation, dry mouth, and drowsiness. These symptoms were related to their health history or seasonal effects besides air-conditioning issues. A majority of occupants have expressed their satisfaction with the building environments and all its environmental parameters. However, a small percentage of respondents have expressed dissatisfaction also which could be related to their individual backgrounds, medical issues, workloads, and attitudes. However, cigarette smoking remains an issue in commercial buildings.