Employees are an important part of generating innovation. The challenge that then arises is how to apply innovation in their respective contexts. In improving the behavior of work innovation, the researcher formulates the existence of variables in the form of increasing knowledge. So this study aims to determine the knowledge-processing capabilities of employees on innovative work behavior mediated by employee creativity. Quantitative techniques are used in this study. In this study, using 6 F&B manufacturing industries, more specifically the large coffee beverage factories in Indonesia, so that the sample in this study were 100 respondents who were employees of these companies. The analysis of this study is a Structural Equation Model (SEM) approach with smart PLS. The result of this research is that environmental dynamism affects innovative work behavior. Knowledge acquisition affects innovative work behavior. Knowledge dissemination affects innovative work behavior. Knowledge utilization affects innovative work behavior. Employee creativity affects innovative work behavior. Environmental dynamism doEmployees are an important part of generating innovation. The challenge that then arises is how to apply innovation in their respective contexts. In improving the behavior of work innovation, the researcher formulates the existence of variables in the form of increasing knowledge. So this study aims to determine the knowledge-processing capabilities of employees on innovative work behavior mediated by employee creativity. Quantitative techniques are used in this study. In this study, using 6 F&B manufacturing industries, more specifically the large coffee beverage factories in Indonesia, so that the sample in this study were 100 respondents who were employees of these companies. The analysis of this study is a Structural Equation Model (SEM) approach with smart PLS. The result of this research is that environmental dynamism affects innovative work behavior. Knowledge acquisition affects innovative work behavior. Knowledge dissemination affects innovative work behavior. Knowledge utilization affects innovative work behavior. Employee creativity affects innovative work behavior. Environmental dynamism does not affect employee creativity. Knowledge acquisition affects employee creativity. Knowledge dissemination does not affect employee creativity. Knowledge utilization affects employee creativity. The results of the mediation hypothesis state that employee creativity is able to strengthen the relationship between knowledge acquisition and innovative work behavior. Employee creativity is not able to mediate the relationship between innovative work behavior and environmental dynamism, knowledge acquisition, and knowledge dissemination variables. It can be concluded that F&B manufacturing companies need to increase knowledge between individuals and perform knowledge processing capabilities to improve employee innovation behaviores not affect employee creativity. Knowledge acquisition affects employee creativity. Knowledge dissemination does not affect employee creativity. Knowledge utilization affects employee creativity. The results of the mediation hypothesis state that employee creativity is able to strengthen the relationship between knowledge acquisition and innovative work behavior. Employee creativity is not able to mediate the relationship between innovative work behavior and environmental dynamism, knowledge acquisition, and knowledge dissemination variables. It can be concluded that F&B manufacturing companies need to increase knowledge between individuals and perform knowledge processing capabilities to improve employee innovation behavior