The health crisis that our country is going through is very difficult to manage and vaccination is of utmost importance to counteract it; however, the logistical process of purchasing and distributing vaccines is very complex. Objective: Therefore, the present research article aims to design a predictive model that influences the logistic response planning for COVID 19 vaccination in the district of San Juan de Lurigancho. Methods: This can be achieved using geographic information systems technology and the implementation of mobile vaccination centers. Results: The results obtained showed the lack of vaccination sites in the district and how this measure generates a great benefit in the most vulnerable population of the study district. In addition, it is positive the results obtained compared to the results of other articles. Conclusions: It is confirmed that the logistic process of vaccination can be improved from the implementation of mobile vaccination centers.