Supply chain network design concerns determining the location and capacity of facilities including manufacturing and assembly plants, warehouses and distribution centres. Greening of supply chain operations is most effective if addressed at the strategic network design phase. This has been an important area of research focus for almost a decade now. One can however argue that a green supply chain design may have impacts on the supply chain resiliency making supply chains less robust to disruptions. Supply chains may face disruptions of various types—noting the increasing occurrence of natural disasters (e.g. floods, earthquakes) and man-made disasters (e.g. strikes, terrorist attacks). Using a modelling approach, this paper aims to investigate how greening of a supply chain design can influence its resiliency to disruptions. An optimisation model is presented that can be used to investigate the economic and environmental tradeoffs of supply chain networks in normal and under-disruption circumstances. Numerical experiments provide interesting managerial insights and practical implications.