Facing the reduced public expenditures, the increasing healthcare costs, and the aging of population, hospitals have been struggling to maintain healthcare quality and improve efficiency while utilizing the available medical resources. However, structured approaches to design healthcare service pathways, which contribute to healthcare efficiency and quality, are not widely available. The platforming thinking has been well investigated in the manufacture industries. With this thinking, product platforms have been developed and applied in companies’ product family development activities. The benefits include meeting diverse customer requirements, reducing time to market, improving product quality, etc. In view of the gains of applying platforming thinking in the manufacture industries, this study proposes to apply it in hospitals as structured approaches to design healthcare service pathways. More specifically, it puts forward a concept of healthcare platform to help hospitals design healthcare service pathways for diverse patients. Modules are defined to model healthcare process upgrade and elimination. Math formulations are developed to model how a healthcare platform is planned and how customized healthcare service pathways can be designed. A case study is conducted in an ophthalmic hospital in central China. The results demonstrate the potential and feasibility of designing healthcare service pathways based on healthcare platforms.