The objective of this study was to analyze, by the finite element method by the commercial code Abaqus 6.11 software, the stress level in the PMMA binder the prosthesis to the acetabulum and the inter-microvoids interaction effects on the mechanical behaviour bone cement. The interface and the free edges are stress concentration seats. At these sites, we assumed the location of microvoids. The interaction of the stress fields of these defects with the free edge and the cement-bone interface generates a significant concentration of shear stress priming generally to the free edges of the structure and leads to the rupture and premature loosening of the cement.