The application of improvement methodologies such as Six sigma enables companies to achieve better performance and quality in their processes, products or services. This paper presents the case of a multinational company in the food industry in Colombia, where a Six sigma project was developed to reduce waste from a production line of toasts. Each one of the DMAIC process phases are developed and evaluated, in order to identify the principles causes of waste in the process. Finally, a 0.5% waste reduction is achieved with the solution presented, producing approximate savings of 136`594.834,4 millions of Colombian pesos per year. Thus, it is shown that Six sigma is a strategy that provides engineering tools and statistical techniques that allows solve organizational problems satisfactorily.