Due to considerable increase in concrete using in different areas of construction industry around the world, an intense need is currently felt for improving concrete properties, especially its durability. Furthermore, the necessity for the new types of concrete with higher durability and better performance for specific purposes, as compared to the available types, is sensed more than ever. The concrete durability, affected by different variables such as compressive strength, electrical resistance and permeability, has already attracted the attention of many researchers. In the present study the effects of adding various nanoparticles to the concrete, changes in the humidity and temperature of the curing surrounding atmosphere are investigated to find out whether they will cause any increase in compressive strength and electrical resistance of concrete and/or any decrease in its permeability. For this study, the Taguchi method is applied as a method of design of experiment to get the optimal level for each variable, followed by applying the regression method to model the variables. Eventually, the final optimal levels for the durability are presented based on the desirability function.