This paper seeks to describe the relationship between the determinants of organizational performance such as entrepreneurial leadership (EL), total quality management (TQM) practices, and innovation management (IM) of Kuwaiti's Small and Medium Enterprises (SMEs).  However, relatively few studies that offer a complete model to fully explain the link between EL, TQM, and IM on SMEs performance. Hence, this study addresses a gap in the literature by providing a conceptual model to illustrate the relationships between these variables. The proposed model also suggested the mediating role of TQM practices and the moderating role of IM on the relationship between EL and organizational performance of SMEs based on the suggestions of the literature. The findings of this study are significant to SMEs in Kuwait on the need to provide an important insight into the concepts of EL, TQM, and IM to improve their performance. Furthermore, the study will serve as additional literature to few studies on Kuwait SMEs performance as a developing country emerging has not been explored.