The increasing number of Covid-19 cases and death rates and the spread across regions and countries indicate that the feed has been extraordinary and has impacted political, economic, social, cultural defense and security aspects, and Indonesia's people's welfare. Referring to the available evidence, Covid-19 is transmitted through close contact and droplet splashes, not through air transmission. The most effective preventive measures in the community: hand hygiene; Avoid touching eyes, nose, and mouth; applying cough etiquette; wearing a mask; maintain a distance (at least 1 meter). The research objective of this study was to analyze the effect of health promotion and personal hygiene on the incidence of Covid-19 through physical distancing in the Central Mamuju Regency. Quantitative research methods with analytical survey methods are used as a research method. Data collection through questionnaire distribution was carried out in Central Mamuju District. The sample was determined by a sampling technique using the Slovin formula, which was then sorted according to the inclusion and exclusion criteria. The model that was successfully collected came from 137 respondents. The analysis used in this research is path analysis. Based on the results of the study, it was found that 1) health promotion did not affect physical distancing; 2) personal hygiene has a positive and significant effect on physical distancing; and 3) Health promotion, personal hygiene, and physical distancing did not have a substantial impact on the incidence of Covid-19 in Central Mamuju District. Health promotion and personal hygiene have a negative but insignificant effect on the incidence of Covid-19 through physical distancing in Central Mamuju Regency.