This study aims to examine and analyze the influence of competence and management quality on the effectiveness of using medical equipment through the electro-medical performance at Makassar City Hospital. The research design used in this study is a survey and path analysis with a quantitative approach in which data concerning the independent variable, dependent variable, and intervening variable are taken simultaneously to determine the direct and indirect effect of the variables to be studied. The population of this study was all 101 electromedical officers scattered in hospitals within the city of Makassar. The number of samples used saturated samples, or total sampling, namely the entire population in the study, was used as a sample with 101 respondents in all hospitals in Makassar City. The results showed that competence on the effectiveness of using medical equipment directly had a negative and insignificant effect and competence of the efficacy of using medical equipment through electromedical performance was negligible. In contrast, the quality of management on using medical equipment through electromedical version both directly and indirectly had a significant positive effect.