This study aims to analyze: (1) the influence of leadership on motivation, (2) the result of incentives on motivation, (3) the impact of motivation on nurses' performance, (4) the influence of leadership on the performance of nurses, (5) The effect of incentives on nurse performance, (6) the impact of leadership on performance through motivation, and (7) incentives on nurse performance through motivation. This research was carried out on all nurses who served in the Makassar General Hospital Labuang Baji inpatient room and was carried out from January 13 to April 13, 2019. The type of research used was quantitative research. This study's population was 154 respondents with a sampling technique using a total sampling of 154 respondents. The data collection technique used a questionnaire. The analysis technique used in this research is path analysis. The results showed that motivation is influenced by leadership and incentives positively and significantly, nurse performance is influenced by leadership, incentives, and motivation positively and significantly, leadership and incentives have a positive but insignificant effect on nurse performance through work motivation of nurses.