Natural disasters that occur have an impact on the agricultural sector. The impact of the disaster on the agricultural community in the form of failed harvests and damage to farming facilities, in addition to causing considerable losses to the community it is also detrimental to the government because in the end it can have an impact on food shortages. The agricultural sector has an important role in West Muna Regency, a sustainable planning is needed and in accordance with the conditions in the region. Therefore, this study aims to analyze agropolitan area planning in the agricultural sector in West Muna Regency based on natural disaster mitigation. The data used in this research is agricultural sector data, especially food crops in West Muna Regency. The Location Quotient method is used to analyze efficient food crop base commodities. Based on the results of the study, it was found that an efficient food plant base commodity was obtained with geographic conditions as an Agropolitan Area. In addition, commodities that are suitable for the disaster that occurred in West Muna Regency were also obtained. Thus the availability of food raw materials is still available and maintained, and can increase competitiveness in the agricultural sector