Industry 4.0 defines the intelligent network and inter-relationship amongst components of production systems, providing digital feedback across the industrial value chain. The pulp and paper production organization execute flexible advanced manufacturing processes i.e. mechanical pulping, chemical pulping, re-pulping of waste paper, rolling and milling, to produce paper products. In this paper, research output of Industry 4.0 in the pulp and paper industry 4.0 is appraised. A systematic literature review of publications from 2007 to 2017, pertaining to key practices of Cyber Physical System (CPS) is conducted. The authors reviewed ninety three publications, utilizing coupled search engines such as open and internet based research search.