Six Sigma DMAIC is a methodology used by business organizations to improve their processes by controlling and reducing variation. In this project, an attempt is made to apply and implement Six Sigma to increase teacher’s awareness regarding diabetic children in primary schools. At first, a pilot test was conducted to identify and prove the existence of problem. The results revealed that 45% of teachers did not know the symptoms of hypoglycemia where 20% of them faced more than 6 cases of diabetic pupils in the schools. Voice of the Customer (VOC) was then gained through a parent survey. The Critical to Quality (CTQ) was then identified as well as the Define Phase was then completed. Moreover, the teacher’s current performance level was measured by distributing a knowledge test and the results discovered that the performance level is 57.7%. Therefore, the team decided to focus on increasing teacher’s awareness by at least 30%. Several tools such as Quality Function Deployment (QFD) and Failure Mode Effect Analysis (FMEA) were implemented in both the Analyze and Measure phases, then the most effective improvements were identified. An educational awareness program was then conducted to introduce teachers to the most important information required to handle a diabetic child. Subsequently, another knowledge test was distributed to identify the improvements in the scores of the teachers. The results, revealed that the awareness level increased from 57.7% to 89.9%, and DPMO reduced from 476190 to 238095. Finally, the Control Phase was completed through introducing an action plan that would maintain the improvements made for more years to come.