Information Technology (IT), by facilitating and accelerating information exchange, enables organization and suppliers to become aware of each other’s needs and meet them in a timely manner which enhances on-time production philosophy. In this respect, a study was conducted with the aim of investigating the role of information sharing in drug supply chain using the views of experts in the field of pharmacy in Tehran and Hormozgan University of Medical Sciences as well as relevant organizations such as drugstores, hospitals, and drug deputies in 1392-1393. The findings revealed that 71% of the experts completely agree with the impact of information sharing on the integration of drug supply chain, and 45% agreed with the effect of information sharing on the efficiency of drug supply chain. Also, 45% of the experts confirmed the effect of information sharing on the performance of drug supply chain. Based on the results of inferential statistics, information sharing has a significant effect on the efficiency, integration, and performance of drug supply chain.