Changes in societal and technological economic systems indicate an industrial revolution. Any industrial revolution comes with implications on the education of its society. There has been an observerable interest in entrepreneurship education since the beginning of the millennium 2000 by institutions of higher education, incubators, development agencies and government in developing countries. The focus of entrepreneurship education has been on opportunity identification, attracting resources and managing risk in a new start-up enterprise. However, the 4th Industrial Revolution changes the narrative of how entrepreneurship education is understood and its future. The 4th Industrial Revolution means change in societal and technological economic systems. The nature of opportunities and how resources for businesses are deployed will also change, hence a need to understand the implications of the 4th Industrial Revolution on Entrepreneurship Education. In this research paper we use a theoretical framework that presents focal themes of Entrepreneurship Education and Industry 4.0. These are contrasted in this paper to derive the implications of Industry 4.0 on Entrepreneurship Education following the research design of this study. The design of this study is a desk review of 50 journal articles on which the derivation of the implications of Industry 4.0 on EE is based. A discussion, conclusion and a direction for future research is provided on this paper.