Online platforms are encompassing different aspects of human’s live including healthcare services. By using advanced technology and online platforms, access to information and reaching out to people across the world has never been easier. Utilizing online communities to gather inputs, ideas and even investments helps users to reach conclusive results faster and cheaper. As well as the vast activities that can be performed with digital technology, many people seek healthcare advice and help through the online platforms. In healthcare systems, one of the most important aspect of the decision-making process is the interaction between doctor and patient. The quality of this interaction has a direct and significant impact on medical, clinical or pharmaceutical decisions and treatments. This paper systematically reviews the application of digital and information technology in diagnostic decision-making process in healthcare systems through using online platforms such as social media.