This paper presents the work of analyzing the process of registering new student candidates at University X through modeling and simulation by using ARENA software. The layout of the student candidates' registration process at the university was observed and analyzed. The data taken is the processing time in each process counter sequence, the number of workers, and the layout arrangement by direct observation using a stopwatch. There are three layout models analyzed, namely the initial layout and two alternative layouts as the development of the initial layout. The results of the simulation for the initial layout model succeeded in reaching the number of enrollments of 443 new students at the same time as the real system, which was 4 hours 30 minutes. The first alternative layout model is simulated by reducing the number of workers less than that in the initial layout model.  Furthermore, the second alternative layout model is simulated for the number of new student candidates increased by 20% from that of the initial model. The results of this study indicate that modeling and simulation using ARENA is very useful in analyzing the registration process of new student candidates to get smoothly, efficiently, and quickly process.