This paper aims at filling the gap between academic and practitioner view and knowledge on modularisation in the oil and gas sector. It shows how a theoretical framework on modularisation has been successfully applied in two case studies. A replicable methodology is given to illustrate how to customize the proposed framework in an operative context. The purpose is to increase both awareness and knowledge of a firm about the potential of the modular approach and to offer a proper support for decision makers along the overall project delivery chain and under the different stakeholders’ point of view. The comparison among theoretical studies about the modular approach and the real practice in EPC field allows finding further tactical and strategic developments of industrial plant projects execution.