Spatial models have attracted considerable interest in the recent economics and econometrics literature, both on an empirical and theoretical level. One of the most widely used spatial models is the single equation model. The following spatial simultaneous equation model can be viewed as an extension of the widely used spatial single equation model and can uses more than one equations. Generalized Spatial three Stage Least Square (GS3SLS) estimator is more efficient than the Other spatial simultaneous model. GS3SLS with weighted matrix as an invers from Distance can give best model than other weighted matrix. By using GS3SLS it can be concluded that there is a relationship of Unemployment Rate and economic growth in East Java.