Tourism agility and resilience are increasingly getting research attention as prominent dynamic capabilities. Furthermore, while studies have explored their development from different perspectives; the importance of IOS appropriation in development of tourism agility and tourism resilience was not explored.  Hence in this study we explore the role of IOS appropriation in the form of five key IOS usage-based capabilities viz IOS use for communication, intelligence, integration, collaboration and coordination in the development of tourism SC agility and resilience. Furthermore, the inter-relationship among these IOS usage-based capabilities were also explored. The study collected perceptual measures from hotel managers and tour managers having sufficient experience in the tourism sector. With 209 completed responses, the data were analysed using partial least squares. The study found IOS use of communication and intelligence as prominent enablers of IOS use for integration, collaboration and coordination. Furthermore, IOS use for integration, collaboration and coordination was found to have prominent influence in the development of tourism SC agility and resilience.